Event Prediction Including Cured Population

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Documentation for package ‘EventPredInCure’ version 1.0

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EventPredInCure-package Event Prediction Including Cured Population
b4pst Function to calculate survival time and censor variables before and post a time lag (delay treatment effect time)
Chen_2016_event_time Function to generate event time in the existence of cured population
Chen_2016_event_time_abovetime0 Function to generate event time based on Chen 2016 method for ongoing subject
Chen_2016_event_time_piecewise_exp_abovetime0 Function to generate event time with piecewise exponential distribution for ongoing subject in the existence of cured population
FH_test Fleming-Harrington weighted log-rank tests
finalData Final enrollment and event data after achieving the target number of events
fitDropout Fit time-to-dropout model
fitEnrollment Fit enrollment model
fitEvent Fit time-to-event model
getPrediction Enrollment and event prediction
interimData1 Interim enrollment and event data before enrollment completion
interimData2 Interim enrollment and event data after enrollment completion
loglik_Chen_exponential Log-likelihood function for exponential distribution with cured population
loglik_Chen_log_logistic Log-likelihood function for log-logistic distribution with cured population
loglik_Chen_log_normal Log-likelihood function for log-normal distribution with cured population
loglik_Chen_piecewise_exponential Log-likelihood function for piecewise-exponential distribution with cured population
loglik_Chen_weibull Log-likelihood function for Weibull distribution with cured population
predictEnrollment Predict enrollment
predictEvent Predict event time for ongoing subjects with or without cured population.
smed Function to output summary statistics from survfit function output
SP_Chen_exponential Survival probability function of the exponential distribution with cured population
SP_Chen_log_logistic Survival probability function of the log-logistic distribution with cured population
SP_Chen_log_normal Survival probability function of the log-normal distribution with cured population
SP_Chen_piecewise_exponential Survival probability function of the piecewise exponential distribution with cured population
SP_Chen_weibull Survival probability function of the Weibull distribution with cured population
summarizeObserved Summarize observed data
test_plot Function to plot KM plot for time-to-event data in simulation
test_procedure Function to provide summary and test statistics based on simulation.
tte Calculating log-rank test p-value, median time from each arm, hazard ratio between two arms, number of subjects and events in time-to-event outcomes.